No. | Schiff base | Solvent | Temp (˚C) | Yield of Ala (%) | S (e.e.%) |
1 | 8a | MeOH | 30 | 50 | 64 |
2 | MeOH | 10 | 29 | 62 | |
3 | MeOH | –10 | 32 | 67 | |
4 | MeOH | –30 | 10 | 50 | |
5 | EtOH | –10 | 33 | 46 | |
6 | 2-PrOH | –10 | 20 | 75 | |
7 | THF | –10 | 24 | 45 | |
8 | AcOEt | –10 | 28 | 71 | |
9 | 8c | MeOH | 30 | 38 | 63 |
10 | MeOH | 10 | 23 | 29 | |
11 | MeOH | –10 | 39 | 77 | |
12 | MeOH | –30 | 8 | 23 | |
13 | EtOH | –10 | 40 | 78 | |
14 | 2-PrOH | –10 | 22 | 42 | |
15 | THF | –10 | 15 | 40 | |
16 | AcOEt | –10 | 25 | 58 |